Calvin Harrison collected four wickets in an innings for the third time in the Vitality Blast season as the Outlaws bundled Durham out 79 runs short of the 222 required for victory at Trent Bridge.
The victory, set up by a swashbuckling Ben Duckett who blazed 74* not from 41 deliveries, rounded off the Outlaws’ North Group stage in style.
Notts cemented their place at the top of the group, having sealed a home-quarter final with a win against Yorkshire.